How the COVID Virus Sneaks Past Immune Defenses

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How the COVID Virus Sneaks Past Immune Defenses
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Just how the COVID virus eludes the human immune system has mystified scientists for close to two years, but now they've uncovered an important clue. Learn more:

It also helps explain why the first outbreak led to much higher death rates and lasted only eight months, while the current pandemic has persisted for two years with many cases being symptom-free — and no end in sight.

That familiar spike protein on the virus' surface enables the cell-to-cell spread. Neutralizing antibodies are less effective against the virus when it spreads through cells. For the study, researchers used non-infectious pseudoviruses, with both kinds of coronavirus spike proteins on their surface.

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