'Globally, more people are exposed to unsafe levels of air pollution than to toxic chemicals in cigarette smoke, and these new data link the importance of addressing climate health to improving human health,' said researcher CharlesSwanton. ESMO22
"If you want to address human health, you have to address climate health first," said Charles Swanton, who led the research team.Experts emphasized the importance of more ambitiously addressing air pollution from fossil fuels after the presentation of a new breakthrough on lung cancer in Paris on Saturday.
The way air pollution causes cancer differs from cigarettes and sunlight. Tobacco smoke and ultraviolet light damage the structure of DNA, creating mutations that cause cancer. Air pollution causes inflammation in the lungs, affecting cells that carry mutations. The team analyzed 463,679 individuals from England, South Korea, and Taiwan, and examined lung tissue samples from humans and mice following exposure to particulate matter, or PM2.5—air particles that are no larger than 2.5 micrometers in diameter.
"According to our analysis, increasing air pollution levels increases the risk of lung cancer, mesothelioma, and cancers of the mouth and throat," noted Emilia Lim, co-first author and postdoctoral researcher at the Francis Crick Institute and UCL."This finding suggests a broader role for cancers caused by inflammation triggered by a carcinogen like air pollution."
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