A huge Danish study shows that up to 30 percent of psychosis diagnoses in young men could have been prevented if these individuals hadn't used marijuana heavily
The French psychiatrist Jacques-Joseph Moreau published a book called Hashish and Mental Illness in 1845, the same year that Scientific American brought out its first issue. In it, he explored his own experiences with the drug cannabis at the Paris-based Club des Hachichins—some of which took place alongside the likes of Victor Hugo, Honoré de Balzac and Charles Baudelaire. Two years earlier Moreau described the “undescribable delights” of a “marvelous substance.
The Danish epidemiology study does not offer hard-and-fast proof of the cannabis-schizophrenia connection, which could be accomplished only through randomized controlled trials. But this link is supported by the fact that marijuana use and potency have risen markedly—from 13 percent THC content in Denmark in 2006 to 30 percent in 2016—alongside a rising rate in schizophrenia diagnoses.
The Danish-funded study, Compton says, raises a number of questions for future research as to whether adolescent male brains are more at risk than female brains for developing psychosis from marijuana or whether men’s levels of exposure to cannabis can explain the difference. David Nutt, a professor of neuropsychopharmacology at Imperial College London and a founder of the nonprofit Drug Science, which provides information about drugs “free from political or commercial influence,” calls the Danish study “intriguing.” But, he adds, “it also raises many more questions.”
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