It can provide new joint biomarkers for depression and CVD, leading to the development of treatments simultaneously targeting the two.
As per rough estimates, 280 million people across the globe suffer from depression, while around 620 million are diagnosed with CVD.Researchers have identified a gene module with 256 genes that are significantly correlated with both depression and cardiovascular diseases .
Both depression and CVD pose a towering problem to global health. As per rough estimates, 280 million people across the globe suffer from depression, while around 620 million are diagnosed with CVD.Several research papers in the past, too, have hinted at a possible link between the two. It is common knowledge that those suffering from depression have a higher risk of becoming a CVD patient. The reverse is also true, as patients suffering from CVD can also go into depression.
The paper provides new markers for depression and CVD and could ultimately help to find drugs to target both diseases.
From the data collected, the dynamic tree-cutting algorithm identified 22 gene modules from the hierarchical clustering of the dissimilarity matrix, containing 14–10,367 highly correlated genes.
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