From politics to the lab: The push for psychedelics in Mass.

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From politics to the lab: The push for psychedelics in Mass.
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New research, a potential state ballot measure and pending decisions from the FDA are putting psychedelics are on a path that could lead them to become an integral part of mental health care in Massachusetts.

Psychedelics are on a path that could lead them to become an integral part of mental health care in Massachusetts.

Opponents of the ballot question told lawmakers decriminalizing a substance doesn't mean it will be safe. They argued there's no conclusive evidence that psychedelics are a beneficial medical treatment, and pointed to studies indicating certain psychoactive substances may "Why nature created plants that would have profound effects on the human brain is unknown, but we're quite certain from the travels and reports and archives of Schultes at Harvard, and the vast ethnobotanical literature mentioning different plants and their uses and properties, that there's more space to explore.

"We can create almost little mini-brains to see how human brain cells respond, and how that is alike or different from the effects of known psychedelics and other psychotherapeutic agents."We can grow a tiny little brain of you. We can take skin cells and transform them into stem cells, and evolve them into brain cells and allow them to grow. And really, even though they're tiny, they'll have the five layers of neuronal tissue that we see in the brain.

"The leading hypotheses — well there are really several. One is that people have a profound experience and from that experience they learn something new that changes their behavior and sense of self, or perspective on the world. That's a profound experience. That experience changes things about people.

"When we opened recruitment to a small neuroimaging study of 20 subjects with treatment-resistant major depression offering a single treatment with psilocybin, hundreds of patients responded, suggesting that there is a large number of patients who are eager for access to psychedelic treatment. "I believe that these molecules that we're exploring in the psychedelic space will provide additional tools for treating people that we haven't been able to help. So I do believe there'll be a useful addition to the pharmacopeia. I don't know that they'll be as miraculous as some people feel. They've been transformational and miraculous for some, and those people have become profound advocates, even to the point of, I think, proselytizing.

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