The tumour-fighting proteins Elephants carry can destroy mutated cells, say scientists. This could explain why Earth’s largest land animals are over five times less likely to develop cancer than humans 🤯 🐘🐘🐘
With an army of tumour-fighting proteins in their genes, elephants could hold the key to curingThe tumour-fighting proteins they carry can destroy mutated cells, say scientists.
‘This intricate and intriguing study demonstrates how much more there is to elephants than impressive size and how important it is that we not only conserve but also study these signature animals in minute detail,’ said the study’s co-author Professor Fritz Vollrath, of the University of Oxford.
But elephants inherit 40 versions of a gene called P53, 20 from each parent. Dubbed the ‘guardian of the genome’, it hunts down and kill cells with faulty DNA.Elephants exhibit high resistance to cancer with less than five percent mortality ‘In humans, the same p53 protein is responsible for deciding if cells should stop proliferating or go into apoptosis but how p53 makes this decision has been difficult to elucidate,’
The study’s lead author Dr Konstantinos Karakostis, of the Autonomous University of Barcelona said: ‘Conceptually, the accumulation of structurally modified p53 pools, collectively or synergistically co regulating the responses to diverse stresses in the cell, establishes an alternative mechanistic model of cell regulation of high potential significance to biomedical applications.’
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