Early-Life Removal of Ovaries Could Bring Faster Aging

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Early-Life Removal of Ovaries Could Bring Faster Aging
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Premenopausal women who have surgery to remove the ovaries (oophorectomy) and fallopian tubes may face chronic medical conditions and a decline in physical functioning, new research warns.

“It was very important that they were seeing more adverse outcomes in terms of the six-minute walk test, because that is a predictor of several other adverse outcomes in the future,” including premature death and physical function, said Dr. JoAnn Manson, a hospital chief at Brigham and Women's Hospital and a professor at Harvard Medical School, who reviewed the findings.

“If you're under the age of 45, they showed in a previous paper from the Mayo Clinic that if you have women taking out their ovaries under the age of 45 and they did not get estrogen, they had about a threefold increased risk of development ofThe ovaries make most of a woman's estrogen, which is key for regulating the menstrual cycle and affects the urinary tract,and blood vessels, bones, breasts, skin, hair, mucous membranes, pelvic muscles and the brain.

“Basically, the whole series of papers that they've done along these lines is to really show that estrogen is important for people," Minkin said. "That's really what itFor women who are thinking about having their ovaries removed, Minkin summed up the current medical thinking. “Most people would advocate leaving the ovaries in until 60 or 65 -- don't take them out even in somebody who's quote unquote. Leave them in there,” she said. “When we have women who are clearly under the age of 50, what are we doing for these young women? Taking out ovaries is not necessarily the greatest thing in the world for their other medical health.”. In that case, ovaries should be removed, she believes.

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