Vitamin B6, widely promoted and taken as a supplement, should carry a warning label about possible nerve problems, according to the CEO of a large contract research lab in Northern California.
Most of the evidence about toxicity, Najafi says, is from case reports. In a 2017 report in a toxicology journal, researchers said more than 50 cases of a sensory nerve pain due to vitamin B6 supplements were reported from 2014 to 2017.
The lowest dose reported to cause adverse effects is 50 mg, Najafi says in his petition, citing a 1987 study that he acknowledges has issues with methodology.There is no need for a warning label on Vitamin B6, say spokespeople from two industry groups that issued statements in response to the petition.
"Vitamin B6 plays a role in numerous functions in the body and can be safely consumed from foods and dietary supplements," says Andrea Wong, PhD, a senior vice president at the Council for Responsible Nutrition."The tolerable upper intake level for vitamin B6 is 100 mg in adults, based on the risk of sensory neuropathy; however, research indicates that sensory neuropathy usually develops at far higher doses.
In another statement, Jay Sirois, PhD, of the Consumer Healthcare Products Association, also cites the limit of 100 mg, set by the Food and Nutrition Board of the National Academies of Sciences, Engineering, and Medicine, and that side effects linked with B6 are ''likely the result of taking extremely high doses for extended periods of"We've known for a long time that vitamin B6 excess can lead to numbness and tingling, but this is predominantly...
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