Early data suggests the omicron subvariant has the ability to overpower some Covid-19 treatments.
and has not yetbeen peer-reviewed, now suggests that the BA.2 subvariant is resistant to sotrovimab, the monoclonal antibody drug from GSK and Vir Biotechnology that's the most recommended treatment in the U.S. against omicron.
“That’s something we’re watching very, very closely,” Dr. Rajesh Gandhi, an infectious-disease specialist at Massachusetts General Hospital, said at a virtual briefing Friday with the Infectious Diseases Society of America. The Biden administration has purchased 600,000 doses of the Lilly drug. About 300,000 treatment courses of the new antibody drug are expected to ship by the end of the month, and another 300,000 in March.Still, Gandhi said emerging data on BA.2 suggess scientists may need to develop new treatments that target parts of the virus that are unlikely to change as it mutates.
He said that if scientists focus only on monoclonal antibody treatments then"we will continue to exhaust our options" because new variants will continue to emerge.
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