Digestive Disorders and Mental Health IBS digestion health mentalhealth
The microbiota-gut-brain axis and neuropsychiatric disordersVariability in the correlations between mental health and gastrointestinal disordersFurther reading
The prevalence of irritable bowel syndrome varies widely. However, it is estimated that the pooled global prevalence is 11.2%, with a higher prevalence in women than men. As irritable bowel syndrome is characterized by chronic abdominal discomfort and pain with associated changes in stool consistency and emptying, it can dramatically reduce the patient's health-related quality of life.
This study highlighted that long-term perturbation to this homeostatic environment fostered by the microbiota-gut-brain axis can contribute to the progression of several disorders as a consequence of alterations in several physiological processes, including the hypothalamic-pituitary-adrenal axis activation, immune function, and associated inflammatory response, and neurotransmitter systems.
The incidence of psychiatric illness and gastrointestinal disorders Approximately 60% of those who suffer from gastrointestinal disorders are found to suffer from one of several psychiatric disorders. Among them, depression and anxiety are the most common comorbidities. Variability in the correlations between mental health and gastrointestinal disorders Relative to anxiety, however, opposite findings have been found for subtypes of irritable bowel syndrome and depression. A meta-analysis reported that patients who suffered from both diarrhea-predominant and constipation-predominant irritable bowel syndrome showed higher anxiety levels. Still, patients with diarrhea-predominant irritable bowel syndrome only appeared to have increased levels of depression.
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