Boston COVID researchers have combined the omicron variant spike protein with the original virus, testing the created strain on mice “to help fight against future pandemics.”
Boston University COVID researchers have combined the omicron variant spike protein with the original virus, testing the created strain on mice “to help fight against future pandemics,” according to BU.
The scientists in BU’s National Emerging Infectious Diseases Laboratories found that all mice infected with only the BA.1 omicron variant had mild cases and survived, while the combined omicron spike protein with original COVID-19 virus strain inflicted severe disease with an 80% mortality rate.
“Consistent with studies published by others, this work shows that it is not the spike protein that drives Omicron pathogenicity, but instead other viral proteins,” said lead study author Mohsan Saeed. “Determination of those proteins will lead to better diagnostics and disease management strategies,” Saeed said.
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