The FDA is set to convene a panel of its outside vaccine advisers later this month to weigh key issues over the future of COVID-19 vaccines, including when and how to greenlight new boosters and changes to which strain the vaccines target.
to weigh key issues over the future of COVID-19 vaccines, including when and how to greenlight new boosters and changes to which strain the vaccines target.New vaccines by nose or mouth
A few of these vaccines have been licensed in other countries, but none in the U.S. — and the data behind them isn't robust, said Dr. John Beigel, associate director for clinical research at the National Institute of Allergy and Infectious Diseases.to pour resources into developing potential next-generation mucosal vaccines to broad clinical trials, Beigel said it would be challenging to"pick the winners" for government backing.
Different companies have researched mucosal vaccines for COVID, but the data is small and fragmented, Beigel said, using different methods and benchmarks. This makes it difficult for scientists to compare early results from labs that have tried out new vaccines in animals. One of the few mucosal vaccines to reach the final stage of clinical trials so far is an intranasal option produced by the company Codagenix. A largebacked by the World Health Organization of the vaccine, which is administered through drops in the nose, is expected to announce results by the end of the first quarter. A trial of the vaccine as a booster was also launched last year in the United Kingdom.
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