COVID-19 Antiviral Pill Rollout Stymied by Shortages as Omicron Rages

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COVID-19 Antiviral Pill Rollout Stymied by Shortages as Omicron Rages
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Pfizer and Merck’s COVID-19 pills that were supposed to be an important weapon against the pandemic in the U.S. are in short supply and have played little role in the fight against the omicron wave of infections.

While the supply is expected to improve dramatically in the coming months, doctors are clamoring for the pills now, not just because omicron is causing an explosion of cases but because two antibody drugs that were once the go-to treatments don’t work as well against the variant.

The Food and Drug Administration authorized the two pills from Pfizer and Merck late last month based on studies showing they cut the risk of severe disease and death when given shortly after symptoms appear. They are the first COVID-19 treatments patients can take at home, and thus could reduce the burden on hospitals.

Pfizer said it is adding capacity: “We expect to use our strong manufacturing capabilities and our extensive supplier network to continue to improve output rapidly.” Since last month, the government has sent states enough Pfizer pills to treat 164,000 people, allocating them by population. That approach is coming under fire from some states with heavier caseloads.

The Food and Drug Administration has approved Merck’s anti-viral COVID-19 pill molnupiravir for emergency use.In Michigan, all initial shipments went to 10 pharmacies in the hardest-hit areas. Pennsylvania, Maryland, Texas and many other states have distributed the pills more widely, so that at least one pharmacy in each county carries the drug.

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