Concerns growing about two studies on drugs for coronavirus

Concerns are mounting about studies in two influential medical journals on drugs used in people with coronavirus, including one that led multiple countries to stop testing a malaria pill.

Tuesday on a study it published May 1 that suggested widely used blood pressure medicines were not raising the risk of death for people with COVID-19.

Although it wasn't a rigorous experiment that could give definitive answers, the study had wide influence because of its size. The World Health Organization said it would temporarily stop a study of the drug, and France stopped allowing its use in hospitals. Dr. Mandeep Mehra of Brigham and Women's Hospital in Boston led both studies, and the authors include Desai Sapan, Surgisphere's founder.

A statement on Surgisphere's site says it stands behind the integrity of its studies, and notes that observational data like what it supplied from electronic health records are not a substitute for rigorous experiments to test a drug.

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