When used together, two drugs that treat the most common leukemia in adults significantly increase survival and lower the risk that the disease will worsen, according to a new study
The interim analysis of a clinical trial for chronic lymphocytic leukemia, published Wednesday in the New England Journal of Medicine, found that the drugs -- ibrutinib and rituximab -- fared better than a combination chemoimmunotherapy that's known to be effective against the cancer.Researchers found that the"risk of progression or death was 65% lower and the risk of death was 83% lower with ibrutinib-rituximab than with chemoimmunotherapy.
For that reason, doctors are looking forward to trials that might pit these drugs head-to-head or in combination. Not only might researchers find a best-yet cocktail, but Shanafelt hopes there's a solution ahead that's chemotherapy-free and doesn't require patients to be on ibrutinib indefinitely.
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