Cancer patients can now be 'matched' to best treatment with DNA and lab-dish experiments

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Cancer patients can now be 'matched' to best treatment with DNA and lab-dish experiments
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Diana Azzam is an Assistant Professor and Research Director of the newly established Center for Advancing Personalized Cancer Treatments (CAPCT) at Florida International University. She has a Masters in Biochemistry from the American University of Beirut, Lebanon and a PhD in Biochemistry & Molecular Biology from the University of Miami, Florida.

Despite many efforts to find better, more effective ways to treat cancer, it remains a leading cause of death by disease among children in the U.S.

In our newly published results of the first clinical trial combining drug sensitivity testing with DNA testing to identify effective treatments in children with cancer, an approach called functional precision medicine, we found this approach can help match patients with more FDA-approved treatment options and significantly improve outcomes.

By submitting your information you agree to the Terms & Conditions and Privacy Policy and are aged 16 or over.How to best match medicines to patients through DNA is still a major challenge. Overall, only 10% of cancer patients experience a clinical benefit from treatments matched to tumor DNA mutations.

Most recently, my team's clinical trial focused on childhood cancer patients whose cancer came back or didn't respond to treatment. We applied our functional precision medicine approach to 25 patients with different types of cancer.

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