Camille Leahy has new hope thanks to an experimental treatment for acute lymphoblastic leukemia, an aggressive blood cancer
A new method of treating cancer has given Camille Leahy the chance to live. After she was diagnosed in 2020 with acute lymphoblastic leukemia, an aggressive form of cancer of the blood, the single mother from Newmarket, Ont., underwent chemotherapy and a gruelling stem cell transplant. But her cancer kept returning.
CAR-T therapy involves modifying a patient’s own immune cells, called T-cells, to recognize and attack their cancer. A patient’s immune cells are collected and brought to a lab, where the T-cells are genetically engineered to produce a receptor on their surface that targets a specific protein on cancer cells. These cells are then delivered back into the patient’s bloodstream.
“You put on the cells into the machine, you put a bunch of reagents and liquid that helps the cells grow, and then, at the end of 12 days, I mean it sounds very simplistic, but it pops out your product” she said. Hamilton Health Sciences’ Juravinski Hospital and Cancer Centre has been treating patients with commercial CAR-T therapy since January, 2020. The treatment, which is covered by the province, relies on pharmaceutical company facilities in New Jersey and California to manufacture CAR T-cells.
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