Quebec-based biopharmaceutical company Medicago and drug maker GlaxoSmithKline says they have achieved positive efficacy and safety results from their Phase 3 trial of their plant-based COVID-19 vaccine.
TORONTO -- Biopharmaceutical company Medicago and drug maker GlaxoSmithKline reported Tuesday positive efficacy and safety results from the Phase 3 trial of their plant-based COVID-19 vaccine.
“In our efficacy analysis, we have not seen any cases of the original strain of COVID-19…so the results show the vaccine is efficacious against all of those variants we have observed during the study,” he said.The vaccine uses plant-based technology to create “virus-like particles,” which are designed to mimic the structure of viruses so that the immune system can recognize them and build an antibody response to them.
Medicago’s vaccine demonstrated 75.3 per cent efficacy against COVID-19 of any severity for the Delta variant, which D’Aoust said is the most widely circulated strain, and 88.6 per cent efficacy against the Gamma variant. No cases of the Alpha, Lambda, or Mu variants were observed in the vaccinated group while 12 cases were observed in the placebo group, the release states.
The Phase 3 study reported no serious adverse events and reactions were “generally mild to moderate and transient,” with symptoms lasting on average from one to three days. Professor of Virology and Immunology at Memorial University Nfld., and Vice President of the Canadian Society for Virology Rod Russell told CTV News in an interview Monday that he was not surprised at news of Medicago’s positive results.
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