Victoria Atkinson is a freelance science journalist, specializing in chemistry and its interface with the natural and human-made worlds. Currently based in York (UK), she formerly worked as a science content developer at the University of Oxford, and later as a member of the Chemistry World editorial team.
The bell-shaped, purple flowers of foxgloves are immediately recognizable, but this beautiful European wildflower is steeped in supernatural mystery. Also known as witches' gloves and dead man's bells, they've been used as both a folk medicine and a poison for centuries, owing to their potent effects on the human heart.
To get to the bottom of this, we first need to understand how a healthy heart works. The heart itself contains thousands of cardiac cells that contract in time to pump blood around the body. Tiny electric signals regulate this pumping action, and every cell is involved in maintaining this electric activity.
Deactivating this pump causes a cascade of chemical problems within the cardiac cells that combine to make the heart suddenly beat much harder and much faster. This disruption in the heart's natural rhythm, a dangerous type of arrhythmia known as ventricular fibrillation, can lead to sudden cardiac arrest and even death."When the chambers of the heart are not contracting regularly, it can't pump blood, and the overall effect is as though the heart isn't beating anymore," Abriel said.
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