President JoeBiden tested positive for COVID-19 again: How common is a 'rebound' infection?
The president emerged from isolation on Wednesday after testing negative for the virus and completing a five-day course of Paxlovid, the antiviral treatment from Pfizer. White House physician Kevin O'Connor said in his Saturday announcement that Biden had increased his testing frequency because of the potential for a rebound infection. Biden continued to test negative on Tuesday evening, Wednesday morning, Thursday morning, and Friday morning, but the virus re-emerged Saturday morning.
Dr. Ashish Jha, the White House COVID-19 response coordinator said back in May that rebound infections were something they were"looking at very carefully," adding that those cases were"not leading to people getting particularly sick." Pfizer's clinical trial for Paxlovid only showed about 1-2% of patients developing a rebound infection. Given reports of rebounds in more than 5% of Paxlovid patients, some experts have suggested the five-day course of the drug is too short to fully eradicate the virus.
A small study conducted by the Mayo Clinic in June found that just under 1% of COVID-19 patients developed rebound infections after taking Paxlovid. Researchers monitored 483"high-risk" patients, and reported that only"a handful" experienced rebounds, 0.8% in total. All of those who tested positive with the illness again eventually recovered, and the symptoms developed during the rebound were"generally mild.
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