An Indian firm starts mass-producing an unproven covid-19 vaccine

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An Indian firm starts mass-producing an unproven covid-19 vaccine
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The big question is when the Oxford group might be able to show that it actually works

ON APRIL 21ST Adar Poonawalla, boss of the Serum Institute of India, one of the world’s largest producers of vaccines, arrived at work full of optimism about a new vaccine for covid-19, created by the Jenner Institute at Oxford University. In normal times the products that Mr Poonawalla manufactures are proven, effective vaccines. They have regulatory approval, and an order has been placed for them. These are not normal times.

He calls the decision a gut feeling and a personal kind of commitment to public health. The arrangement is not a contractual one, but a “gentleman’s agreement”, says Adrian Hill, head of the Jenner Institute. A number of other companies, as yet undisclosed, are working on agreements with Oxford to produce the vaccine. “No single company can produce the necessary doses and no company should have that authority,” Mr Poonawalla said.

In the week since the decision was taken to mass-manufacture the new vaccine, the Serum Institute has been moving at an impressive clip. It has come to an unwritten agreement with Oxford University, designed a trial to be run in India that will allow the vaccine to obtain a licence, identified the buildings it will use and has started making arrangements to import the vaccine.

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