Alzheimer's disease annihilates the brain cells that keep us awake, scientists believe

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Alzheimer's disease annihilates the brain cells that keep us awake, scientists believe
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Sleep problems can appear in those with Alzheimer's before memory problems show, a scientist told Newsweek.

Newsweek

that people who develop Alzheimer's usually see changes in their sleep patterns years before they show memory changes, tending to sleep more during the day, taking naps, feeling sleepy, or waking up during the night, causing fragmented sleep. "Besides being very annoying and impacting the person's quality of life, it was unclear if this sleep dysfunction was a risk to develop Alzheimer's or even an early symptom," explainedPast studies suggested that fragmented sleep was caused by mechanical problems leading to sleep apnea. This in turn was thought to cause a build-up of amyloid, affecting brain waves and causing more sleep problems. It was thought daytime sleepiness compensated for the lack of sleep.

"Our study shows that actually, the daytime sleepiness is a primary event caused by degeneration of the wake-promoting neurons rather than a reaction to the fragmented sleep, as such, the treatment should be different." Instead of attempting to clear"The study supports the idea that sleep dysfunction is a manifestation of Alzheimer's pathology buildup in the brain, rather than a risk factor. It opens opportunities to treat the cause rather than the symptoms," she said.

"There is no method available to measure individual neuronal function in humans because it requires introducing electrodes in the brain of living people," she explained.said:"At this point, it is too premature to get screened for Alzheimer's because of excessive napping because there is no treatment."

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