An analysis of patients critically ill with COVID-19 finds that 80% had acute kidney injury (AKI) and that patients with AKI had higher ICU mortality compared to patients without. The findings are published in Crit_Care.
]. We did not compare the occurrence of ICU-acquired infections in the first versus the second wave which could also have contributed to ICU mortality.We conducted a multicenter study including seven large ICUs in Flanders. Using electronically recorded data, we collected a large dataset including hourly UO during 21 days of ICU admission which made it possible to detect AKI patterns and differences in diagnosis depending on the used AKI criterion in critical COVID-19.
Follow-up at 30 days was only available in two-thirds of patients, and long-term follow-up data at, for example, 90 days was unavailable which limits conclusions about long-term outcomes. Kidney outcomes were pragmatically assessed until up to 21 days after ICU admission; therefore, the presented rates of AKD and kidney recovery as well as duration of KRT could be underestimated.
Differences in treatment of COVID-19 patients within centers could be present which is inherent to the multicentric design. We included academic and non-academic centers as well as several types of ICU . Since we aimed to give a global picture of COVID-associated AKI in Belgium, and given the fact that some centers had more than 1 ICU, we did not correct for a potential center effect in our analysis.
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