Scientists say rare genetic variant may explain why some women don't need epidurals during childbirth
might be carriers of a rare genetic variant that gives them a much higher threshold for pain, scientists have discovered.
Scientists put a group of women, all of whom gave birth without requesting pain relief, through a number of exercises to test their resistance to discomfort, including applying heat and pressure to their arms and asking them to plunge their hands into icy water. "When we tested these women, it was clear their pain threshold was generally much higher than it was for other women," said Lee, a lecturer with the University of Cambridge's division of anaesthesia.
"Sensitivity of this gatekeeper to electric signals that had the ability to open the gate and turn nerves on was reduced by the rare variant," the researchers found.
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