We need to change the way people are talking about and responding to depression that is difficult to treat. Here's why.
ideation. These conditions are badly underserved—with little research-based evidence and poor outcomes. For many, antidepressants are accessible, inexpensive, and effective, but patients with conditions like TRD often find themselves out of options., it’s a reality. Pharmaceutical companies have traditionally steered away because it’s so difficult to treat.
Patients have shared with me how they learned that they could be denied access to a clinical trial, or even to get care, if they were forthright about their multiple treatment failures or the persistence of their suicidal thoughts. One patient was told, “You don’t have depression, because antidepressants aren’t helping you.” Their stories are heartbreaking, and psychiatrists need to do better at making sure their conditions are researched and understood.
conditions; prior experience with treatments. Ignoring these variables—as is the case too often—lessens the likelihood that a treatment strategy is likely to help.Patients are desperate for options.
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