More than a year after people began rolling up their sleeves for cutting-edge coronavirus shots, a new vaccine — this one based on a classic, decades-old technology — is expected to begin rolling out in the United States this summer.
An agency review released Friday said that testing and submission of manufacturing information about the vaccine was “still in process” and would be essential “to ensure the vaccine’s quality and consistency for authorization.” A meeting of Centers for Disease Control and Prevention vaccine advisers, a critical step before a vaccine becomes available, has not been scheduled yet.
Those moth cells are tiny vaccine factories, churning out coronavirus spike proteins found in the newest omicron subvariants, BA.4 and BA.5. Even as Novavax scientists wait for their first-generation vaccine to be authorized — based on earlier versions of the virus — they are working on new formulations to be ready for wherever the pandemic swerves next.— underscores the speedy development of the first vaccines.
The newer mRNA vaccines instruct cells inside the body of vaccine recipients to build the coronavirus spike protein. The J&J shot uses a harmless virus to spur cells to churn out the spike protein. Novavax, by contrast, manufactures and purifies the coronavirus spike proteins in a laboratory. Gale Smith, Novavax’s chief scientist, said he started working on the technology in the early 1980s as a graduate student.
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