Researchers find promising treatments for weight loss and binge-eating
In the study, 136 individuals with binge-eating disorder were randomized to one of four groups:Binge eating outcomes showed promising results for both treatments: 31 percent stopped binge eating with medication, 37 percent stopped with BWL plus placebo, 57 percent of people stopped in the group that got both active treatments, and only 18 percent stopped with placebo alone.
Both the medication and the therapy were also effective for weight loss. Whereas only 12 percent lost more than 5 percent of their body weight in the placebo group, 19 percent lost more than 5 percent with mediation alone, 31 percent with BWL and placebo, and 38 percent when they received both active treatments.
Statistical testing indicated that medication was significantly more effective than placebo for remission from binge eating, and that BWL was significantly more effective than no BWL for both binge eating and weight loss.Although both treatments are promising, especially BWL—which showed statistically significant effects on both body weight and binge eating in this study—there are some words of caution for those thinking to use either or both of these treatments with their patients.
For people with binge-eating disorder, rebound weight gain after weight loss can be dangerous: the weight comes back on fast with bingeing, and people can get caught in a vicious yo-yo dieting cycle. This study was only 16 weeks and we don’t yet know what the long-term outcomes will be for people for either treatment.On the plus side, these treatments might offer something new that the field desperately needs.
It seems promising that both behavioral weight loss therapy and naltrexone-bupropion could be considered reasonable treatment choices for people who are trying to recover from binge-eating disorder.Carlos M. Grilo, Ph.D., Janet A. Lydecker, Ph.D., Sarah K. Fineberg, M.D., Ph.D., Jorge O. Moreno, M.D., Valentina Ivezaj, Ph.D., Ralitza Gueorguieva, Ph.D. Naltrexone-Bupropion and Behavior Therapy, Alone and Combined, for Binge-Eating Disorder: Randomized Double-Blind Placebo-Controlled Trial.
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