The mRNA vaccine, known as BTN116, developed by the German biotechnology company BioNTech, is the first of its kind and has entered phase 1 clinical trials in seven countries.
Patient Janusz Racz receives an injection of a BioNTech mRNA cancer immunotherapy for non-small cell lung cancer - known as BNT116 - from Keenjee Nama, senior research nurse at the University College London Hospital clinical research facility in central London, as part of the first clinical trial for the lung cancer immunotherapy in the UK.
But the mRNA technology could represent the next major advancement in cancer treatment by training the immune system to target and fight lung cancer cells, Lee said.The development of the lung cancer vaccine began four years ago, following the successful creation of the COVID-19 mRNA vaccine by BioNTech-Pfizer and Moderna, Lee explained.
“So we’re going to use that very simple technology to target the cancer protein, so we identified a common protein in lung cancer patients… and there are many other proteins as well for melanoma and other cancers… but this is a lung cancer patient. We’re going to raise this mRNA vaccine against the protein and then it will hunt the lung cancer.”The mRNA vaccine needs to be in combination with other treatments, like chemotherapy, depending on how severe the cancer is.
“I thought it over, and … decided to take part because I hoped it would provide a defense against cancer cells. But I also thought that my participation in this research could help other people in the future and help this therapy become more widely available,”UCLH consultant medical oncologist Siow Ming Lee and Dr Sarah Benafif talking with patient Janusz Racz before receiving an injection of a BioNTech mRNA cancer immunotherapy.
COVID-19 Lung Cancer Vaccine MRNA Health World
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